Influenza: Antivirale Chemotherapie mit Neuraminidasehemmern erst nach Durchführung positiver Influenza-Schnellteste verordnen
Alexander Mauckner und Wilfried Soddemann
Influenza: Order of antiviral chemotherapy with neuraminidase inhibitors only after the accomplishment of positive rapid diagnostic test for influenza
During the annual influenza seasons the diagnoses in doctor’s offices and hospitals are supported through nationwide early warning systems by Roche (RealFlu) and the German “Arbeitsgemeinschaft Influenza (AGI)”.
The significance of these early warning systems though is too little differentiated to reason a qualified diagnosis.
Regarding the laboratory-diagnostically confirmed influenza-positiv rate with an average <50% during the influenza season 2006/2007, it can be estimated that in 50 % of the clinical influenza diagnoses the chemotherapy with neuraminidase inhibitors like Zanamivir (Relenza®) and Oseltamivir (Tamiflu®) was ordered without given indicators.
Today rapid diagnostic test for influenza with great sensitivity and specificity are available which, depending on the manufacturer and the order quantity, cost between 13 EUR to 17 EUR. They can be accomplished also in medical offices within 20 minutes.
Their application is being advised before the medication with of neuraminidase inhibitors.
For reasons of the more appropriate indication based on an more assured diagnoses the Robert Koch-Institute Berlin (RKI) ought campaign for rapid diagnostic test for influenza with the same intensity as it has done so far for the influenza immunisation and the stocking as well as the medication with neuraminidase inhibitors.